5-MeO-DMT is one of the most potent psychedelics you can consume, and the experience can be intense and powerful in both positive and negative ways. Though everyone will undergo a unique and individual experience, there are some general things you can expect.
Vaporizing or smoking 5-MeO-DMT powder is the most common route of administration. The effects are usually felt within the first 30 seconds after consumption, peaking from 1-15 minutes and lasting for up to half an hour. When taking synthetic 5-MeO-DMT, a threshold dose is around 1-2 mg, while a moderate to strong dose is 5-10 mg.
When swallowed, doses are generally higher, but also show generally unreliable results. Other less common routes of administration include sublingual (under the tongue) and injection.
The effects of 5-MeO come on strong, often with a loss of physical coordination and control. Users experience bright colors, moving environments, or recursive patterns, and perhaps even “environmental orbism” at higher doses. However, visual effects are limited. Unlike DMT, 5-MeO-DMT isn’t known for its visionary properties. The experience is more often described as a “perspective shift” characterized by physical, emotional, and conceptual effects.
One of the most common features of the 5-MeO experience is the enhancement of tactile awareness, which can reach the point of sensory overload. The body may also feel heavier. Intense emotions are typical, ranging from extreme fear to euphoria.
During the onset, anxiety or excitement are often felt. It’s also common to experience an overwhelming sense of oneness with the universe, or a sense of being outside of time and space while simultaneously experiencing the totality of both.
