DMT is a white crystalline powder that is derived from certain plants found in Mexico, South America, and parts of Asia, such as Psychotria viridis and Banisteriopsis caapi.
It is typically consumed in the following ways:
-vaporized or smoked in a pipe.
-consumed orally in brews like ayahuasca.
-snorted or injected on rare occasions.
The chemical root structure of DMT is similar to the anti-migraine drug sumatriptan, and it acts as a non-selective agonist at most or all of the serotonin receptors, particularly at the serotonin 5-ht2a receptor. Serotonin is a neurotransmitter that has a large effect on the majority of our brain cells.
There is some evidence that DMT is also produced endogenously. In other words, it is produced naturally in the body, specifically in the pineal gland in the brain.
When smoked, the average dose of DMT is believed to be somewhere between 30 to 150 milligrams (mg), and the onset of action can be felt almost instantly. The effects peak and plateau for 3 to 5 minutes, and gradually drop off with the duration of effect totalling 30 to 45 minutes.
When consumed as a brew, the dose is between 35 to 75 mg. Effects begin after 30 to 45 minutes, peak after 2 to 3 hours and are resolved in 4 to 6 hours.
The main effect of DMT powder is psychological, with intense visual and auditory hallucinations, euphoria, and an altered sense of space, body, and time.
Many users describe profound, life-changing experiences such as visiting other worlds, talking with alien entities known as “DMT elves” or “machine elves,” and total shifts in the perception of identity and reality.
When smoked, it produces brief yet intense visual and auditory hallucinations that have been described by users as an alternate reality, otherworldly, or a near-death experience.
Depending on the individual user, the experience can range from intensely exciting to overwhelmingly frightening. The experience can be so powerful that users may have difficulty processing and integrating the “trip” into their real life.